News

February 2024: Congratulations to Cameron for receiving the 2024-2025 University Graduate Continuing Fellowship. 

​

January 2024: Joel Cepeda joined the lab. Joel is the first year CBMC graduate student. Welcome Joel. 

​

January 2024: Congratulations to Ying Peng's publication in Chemical Research in Toxicology Ying developed a LC-MS/MS workflow to characterize 3'-histone-DPCs and showed that these adducts are endogenous DNA lesions in HEK293T cells. 

​

August 2023: Xiaoying, Cameron, and Ying presented their work in 2023 Fall ACS meeting. Both Xiaoying and Cameron won the Outstanding Oral Presentation Award from TOXI. Congratulations!

​

May 2023: Congratulations to Ying Peng's publication in Bioconjugate Chemistry. Ying developed a chemical approach to synthesize stable and site-specific 3'-end DNA-histone cross-links, and demonstrated that the DPC repair efficiency is highly affected by the local protein environment, and prior DPC proteolysis facilitates the repair.

 

April 2023: Congratulations to Xiaoying Wei's publication in Biochemistry. Xiaoying demonstrated that Poly [ADP-ribose] polymerase 1 incises abasic sites and covalently cross-links to 3′-DNA termini via cysteine addition not reductive amination. 

​

April 2023: Congratulations to Cameron Bryan's publication in DNA Repair. Cameron showed that apurinic/apyrimidinic endonuclease 1 repairs abasic site-mediated DNA-peptide/protein cross-links. 

​

February 2023: Congratulations to Xiaoying for receiving the 2023-2024 University Graduate Continuing Fellowship.